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Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
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在毛囊插入手术后的冠状腺新血管化.

Alberto Quarta1, Lisa Toto, Maria Ludovica Ruggeri

  • 1Department of Sciences, Ophthalmology Clinic, National Center of High Technology in Ophthalmology, Gabriele D'Annunzio University, Chieti, Italy.

Retinal cases & brief reports
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概括

状新血管化 (CNV) 可能发生在斑点塞手术后. 倒置的内部限制膜手术由于排泄活性和纤维化导致视觉结果不佳,而人类胚胎膜 (hAM) 程序的结果各不相同.

关键词:
一个ILM的倒置.冠状腺新血管化 冠状腺新血管化人类的羊水膜膜.黄斑孔是一个巨大的洞.

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科学领域:

  • 眼科医生 眼科 眼科
  • 视网膜外科手术 视网膜外科手术
  • 血管生物学 血管生物学

背景情况:

  • 黄斑塞手术用于全厚黄斑孔.
  • 胆道新血管化 (CNV) 是一个潜在的并发症.
  • 这项研究研究了在反向内部限制膜和人类羊水膜 (hAM) 程序后的CNV.

研究的目的:

  • 报告和描述在黄斑塞手术后的胆道新血管化 (CNV).
  • 详细介绍使用反向内部限制膜片与hAM移植的情况.

主要方法:

  • 追溯的,观察性的案例系列.
  • 多式成像:OCT,OCT血管造影,光素血管造影/ICGA.
  • 对CNV特征和视力敏度的分析.

主要成果:

  • 在这四个病例中,全中都出现了 CNV (两个耐火,两个主要的黄斑孔).
  • 倒置片病例具有高的排泄性/纤维性潜力,抗VEGF反应有限.
  • hAM病例显示含有或迟泄漏的CNV;视力敏度很差 (20/120-20/200).

结论:

  • 倒置手术后的CNV与由于排泄和纤维化而导致的叶干涉和视力低下有关.
  • 密切监测CNV对于黄斑插头手术患者至关重要,特别是在倒置的板.
  • 在hAM移植体内的CNV可以在没有显著的排泄的情况下发生,这与周围hAM缩有关.