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Updated: Sep 20, 2025

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

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在血管光滑肌细胞中恢复胆固醇外流,通过肝 X 受体激活转化为泡细胞

Carla Borràs1, Noemí Rotllan2, Raquel Griñán3

  • 1Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain; Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, CIBERDEM, Madrid, Spain.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|May 22, 2025
PubMed
概括

肝脏X受体 (LXR) 的激活增强了从血管光滑肌细胞 (VSMC) 到便的逆胆固醇运输. 将LXR激动剂与ACAT抑制剂结合起来,可以通过恢复泡细胞中的胆固醇平衡来治疗动脉样硬化.

关键词:
胆固醇 胆固醇 胆固醇在 HDL 和 HDL 之间.肝脏的X受体是一个X受体.我们的老鼠是老鼠.逆转胆固醇运输是指逆转胆固醇运输.血管光滑肌肉细胞 血管光滑肌肉细胞

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