基于智能手机的便测试的性能用于结肠直肠癌查:基于人口的研究
Michael Hoffmeister1, Teresa Seum2, Leopold Ludwig3
1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
概括
一个新的基于智能手机的便免疫化学测试 (FIT) 用于结直肠癌 (CRC) 查是实验室FIT的可行的替代方案. 这种创新的CRC查方法证明了与传统测试相比的诊断性能.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 医疗技术 医疗技术 医学技术
背景情况:
- 如果用户友好,非侵入性结肠直肠癌 (CRC) 查可以增加参与率.
- 基于智能手机的便免疫化学测试 (FIT) 提供了直接的CRC查的潜力.
研究的目的:
- 评估基于智能手机的FIT用于CRC查的可行性和诊断性能.
- 为了将基于智能手机的FIT与基于实验室的FIT进行比较.
主要方法:
- 该BLITZ研究招募了计划在德国南部 (2021-2023) 接受查结肠镜检查的个人.
- 参与者提供了基于智能手机和实验室的FIT.
- 可行性通过问卷进行评估;性能按敏感性,特异性和ROC措施进行评估.
主要成果:
- 55%使用基于智能手机的FIT,其中76%提供了有效的结果,98%使用了实验室FIT.
- 89%的人认为基于智能手机的FIT是一种有用的替代方案.
- 与实验室FIT相比,基于智能手机的FIT显示了相似的敏感度 (28%) 和相同的特异性 (92%) 对于晚期瘤 (34%的敏感度,92%的特异性).
结论:
- 基于智能手机的FIT是用于CRC查的实验室FIT的可行和有用的替代方案.
- 该技术的诊断性能与传统方法相提并论.
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