在用移植后的环酸胺移植全基血造细胞移植后发生的阴侧阻塞综合征

Aitana Balaguer-Roselló1, Juan Montoro2, Marta Villalba3

  • 1Hematology Department, Hospital Universitari i Politècnic La Fe, València, Spain; Instituto de Investigación Sanitaria La Fe, València, Spain; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC CB16/12/00284, Instituto Carlos III, Madrid, Spain.

概括

阴道阻塞综合征/静脉闭塞性疾病 (SOS/VOD) 是一种可控的并发症,在使用移植后环胺 (PTCy) 的全源造血细胞移植 (HCT) 后出现. 关键的风险因素包括先前的移植和较高的CD3+细胞剂量,尽管严重的病例,死亡率相对较低.

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