患有胃症的儿童的神经发育:一个范围审查
Bianca de Moraes Rego Martins1, Nathalia Cristina Oliveira de Souza2, Maria Dalva Barbosa Baker Méio3
1Department of Surgery, Surgical NICU, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. martinsbianca@hotmail.com.
Pediatric research
|May 22, 2025
概括
患有胃症的儿童的神经发育显示出混合的结果,一些研究报告了正常发育,而另一些研究表明有延迟. 复杂的胃分裂可能会给神经发育障碍带来额外的风险.
科学领域:
- 儿科手术 儿科手术
- 发育儿科 发育儿科
- 新生儿科学 新生儿科学
背景情况:
- 胃,一种先天性腹壁缺陷,对婴儿神经发育存在潜在风险.
- 内在因素 (胎液暴露) 和外在因素 (住院治疗,疼痛) 都可能影响神经发育.
- 增加的生存率需要了解长期的神经发育结果.
研究的目的:
- 进行现有文学关于神经发育的孩子出生与胃.
- 分析运动,认知和语言领域的神经发育结果.
- 在这个人群中确定与神经发育迟缓相关的因素.
主要方法:
- 对过去10年发表的研究进行范围审查.
- 使用关键词搜索主要数据库: "胃", "神经发育", "损伤", "运动延迟" 和 "语言延迟".
- 包括的研究仅集中在胃,不包括其他病理.
主要成果:
- 包括11项研究,主要是病例系列 (n=7),参与者的年龄从12个月到10岁.
- 关于神经发育的发现引起争议,一些研究报告了正常发育,而另一些研究表明跨领域的缺陷.
- 综合性胃肠分裂被确定为神经发育迟缓的潜在额外危险因素.
结论:
- 目前的证据不足以最终得出结论,即胃化是否会对神经发育产生负面影响.
- 复杂的胃似乎是神经发育迟缓的额外危险因素.
- 过早生育和怀孕前小是评估神经发育的重要混因素;需要进一步进行高质量,长期的研究.
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