通过CLK1-SRSF1拼接机器,YTHDC1协调瘤性拼接,以调节割抵抗性前列腺癌的进展

Parth Gupta1, Devesh Srivastava1, Vinayak Nayak1

  • 1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, 502285, India.

概括

雄激素受体变体7 (AR-V7) 驱动前列腺癌的进展和酶胺耐药性. 向YTHDC1RNA结合蛋白可以通过降低AR-V7水平来恢复恩扎拉胺敏感性.

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