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Updated: Sep 20, 2025

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds
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Uhrf1下调促进β细胞脱差,通过降低2型糖尿病中的Foxo1表达来促进β细胞脱差

Lanfang Fu1, Juyun Zhang1, Zhu Lin1

  • 1Department of Endocrinology, Haikou People's Hospital, Haikou, China.

Journal of diabetes investigation
|May 23, 2025
PubMed
概括

与PDH和戒指域1 (Uhrf1) 具有乌比奎丁类的表观遗传调节器影响叉头盒o1 (Foxo1) 表达. Uhrf1 knockdown 通过改变 Foxo1 促进剂甲基化,促进了 2 型糖尿病中小岛 β 细胞脱差.

关键词:
2 型糖尿病 2 型糖尿病时间表 Uhrf1在β细胞脱差分化的过程中,β细胞脱差分.

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