相关实验视频

Updated: May 5, 2026

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

案例报告:针对非霍奇金淋巴瘤的双特异性CD20/CD30向化体抗原受体T细胞疗法

Yuejiao Huang¹, Yiming Gong², Xiang Liu²

¹Department of Hematology, Affiliated Hospital of Nantong University, Nantong, China.

Frontiers in immunology

|May 23, 2025

概括

一种新的CD20/CD30导向的CAR T细胞疗法在治疗复发性卵泡淋巴瘤方面显示出前景. 一名患者在两次输液后实现了完全缓解和持续的无病生存,没有观察到细胞因子释放综合征或神经毒性.

科学领域:

在瘤学瘤学.
免疫治疗是一种免疫疗法.
细胞疗法细胞疗法

背景情况:

针对CD19的CAR T细胞疗法对B细胞恶性瘤有效,但由于CD19抗原损失而面临挑战.
针对CD19的治疗后复发或耐药性疾病需要替代治疗策略.
针对替代抗原的CAR T细胞的发展对于克服治疗耐药性至关重要.

关键词:

用CAR T细胞疗法进行治疗.CD20 CD20 是一个CD20 CD20 是一个CD20.CD3030 是一个 CD3030 是一个 CD30.两种特定的CAR T T.转变的毛囊性淋巴瘤

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Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy

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Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

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