超声响应纳米武器:用于癌症声动疗法的共价有机框架
Yu Zhang1, Chunyuan Hou1, Bin Zhu1
1School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. luojun@njust.edu.cn.
Journal of materials chemistry. B
|May 23, 2025
概括
联有机框架 (COF) 在癌症治疗中显示出非侵入性声动疗 (SDT) 的巨大前景. 本综述总结了COF声敏剂及其在增强SDT疗效和组合疗法的作用.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 在瘤学瘤学.
背景情况:
- 声动疗 (SDT) 提供非侵入性,低毒性癌症治疗,通过深层组织透.
- 协价有机框架 (COF) 正在成为SDT中的多功能工具,因为它们具有显著的特性.
- 基于COF的SDT的研究正在迅速扩大,需要进行全面的审查.
研究的目的:
- 为提供基于COF的声动力疗法进展的全面审查.
- 阐明SDT的基本原理,包括超声波化和声动力学效应.
- 总结COF基声敏剂的化学,设计,合成和应用.
主要方法:
- 审查关于COF和SDT的现有文献.
- 对COF结构,合成和声敏化特性进行分析.
- 检查COF在联合和协同癌症治疗中的应用.
主要成果:
- 由于COF具有显著的潜力,可以作为增强SDT的声敏化剂.
- 基于COF的SDT显示出改善治疗结果的希望,并使联合治疗成为可能.
- 该综述详细介绍了各种COF声敏器的施工策略和性能.
结论:
- 基于COF的SDT是一个快速发展的领域,在癌症治疗方面具有显著的潜力.
- 对COF声敏剂和联合疗法的进一步研究可以带来临床益处.
- 应对当前的挑战和探索未来的机遇对于推进基于COF的SDT至关重要.
相关概念视频
02:57Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
01:17Ultrasonography
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
During an ultrasonography procedure, a handheld device called a...