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Updated: Sep 20, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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基因型特异性心肌病的结果

Valerio Pergola1,2, Alessandro Trancuccio1,3, Deni Kukavica1,3

  • 1Molecular Cardiology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy (V.P., A.T., D.K., A.M., C.N., G.G.S., K.S., M. Memmi, P.G., A.C.L., R.B., M. Morini, M. Marino, S.G.P.).

Circulation
|May 23, 2025
PubMed
概括

德斯莫索姆基因变异 (DGV) 影响心律失常的结局. DSP和PKP2基因的特定变异,以及男性性别和双重DGV,增加了危及生命的失律和心力衰竭的风险.

关键词:
心肌疾病死亡,突然,心脏病基因型没有风险

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