健康衰老对食期间舌动力学的影响
Shreyas Punacha1, Kevin Huang1, Fritzie I Arce-McShane1,2,3
1Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, Washington, USA.
Journal of oral rehabilitation
|May 23, 2025
概括
老龄化会损害食期间的舌头和下巴协调. 较老的子表现出舌头运动一致性降低和舌头活动相对于下巴运动的延迟,这表明神经退行性疾病 (如阿尔茨海默氏症) 的潜在生物标志物.
科学领域:
- 神经科学是一个神经科学.
- 生物力学 生物力学
- 老年学是指老年学的学科.
背景情况:
- 与年龄相关的口腔健康问题与阿尔茨海默病 (AD) 和帕金森病 (PD) 有关.
- 在健康与病态衰老中区分口腔运动功能障碍是具有挑战性的.
- 在健康的衰老中,对口腔运动行为的神经机械控制是不太了解的.
研究的目的:
- 评估舌头和下巴动态的与年龄相关的变化.
- 为了研究非人类灵长类动物在自然养行为中的这些变化.
主要方法:
- 使用高分辨率双平面视频放射和X射线运动形态的重建 (XROMM).
- 在年轻和年长的 rhesus macaques 中追踪了 3D 舌头和下巴运动.
- 评估了舌头的刻板印象,速度,舌协调和食性能.
主要成果:
- 较老的在时表现出减少了舌头运动的刻板印象.
- 年龄较大的受试者在舌头运动中相对于部运动有较大的滞后.
- 食性能指标,如操纵,和吞时间受到影响.
结论:
- 研究结果表明,与年龄相关的舌头和下巴动力学变化,表明舌头-下巴协调受损.
- 这些神经机械变化可能成为早期AD诊断的潜在生物标志物.
相关概念视频
Deglutition
2.6K
Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
2.6K
Assessment of the Mouth
434
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
434
Tongue
1.6K
The human tongue is a fascinating and complex organ, responsible for various essential functions such as swallowing, speech, and taste. It is also subject to various conditions and diseases. In this article, we delve into the anatomy of the tongue, its roles, and some common conditions that can affect it.
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
1.6K
The Effect of Aging on Tissues
2.6K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.6K
The Tongue and Taste Buds
37.5K
The surface of the tongue is covered with various small bumps called papillae, which either distribute what has been ingested (filiform papillae) or contain the sensory taste (or gustatory) receptor cells (fungiform, circumvallate, and foliate papillae). Embedded within each taste-related papilla are the taste buds—clusters of 30 to 100 gustatory receptor cells.
37.5K
Cranial Nerves: Types Part II
2.9K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
2.9K


