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声场启用聚合物纳米粒子沉积到容器壁上,以增强药物输送

Jianlei Wu1, Liang Zhao2, Evan H Dubrunfaut1

  • 1Department of Chemical and Biological Engineering, Villanova University, Villanova, Pennsylvania 19085, United States.

Nano letters
|May 23, 2025
PubMed
概括

低频声场增强了聚合物纳米粒子 (NP) 传递到血管壁,改善了向治疗. 这种方法控制了NP生物分布,用于组织特定的处理,而不会改变NP表面的化学成分.

关键词:
声学场的声学场是指声学场的药物输送是药物输送的过程.聚合纳米颗粒的聚合物.组织工程是组织工程.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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