局部 gentamicin 在预防网修复期间手术部位感染的有效性:发展中国家的经验
Mohamed Daffalla-Awadalla Gismalla1,2, Monzer Mohammed Abdallah Ibrahim3, Mohammed Abdelhaleem Mahmoud4
1Department of Surgery, Faculty of Behari, Khartom North, Sudan. mohadaff22@gmail.com.
概括
在网修复后,局部 Gentamicin 并没有显著减少表面手术部位感染 (SSI). 这项研究发现,接受局部 gentamicin 和不接受的患者之间的感染率没有显著差异.
科学领域:
- 手术创新 在外科创新.
- 预防传染病 预防传染病
- Hernia 修复技术 的修复技术
背景情况:
- 在全球范围内,用于 inguinal 和 ventral 的标准是网状修复.
- 表面的手术部位感染 (SSIs) 正在增加网格修复后的并发症.
- 这项研究调查了局部 gentamicin 在预防 SSI 的作用.
研究的目的:
- 评估局部 gentamicin 在减少表面 SSI 的有效性.
- 为了比较接受带有或没有局部 gentamicin 的网状组织修复的患者的感染率.
- 在手术中提供SSI预防的最佳实践信息.
主要方法:
- 展望,横截面,比较研究 (2022年7月 - 2023年3月).
- 197名患者接受了因 inguinal 或 para-umbilical 的选择性网状修复.
- 两组:对照组 (没有局部 gentamicin) 和研究组 (局部 gentamicin).
- 在术后第1,7和30天评估手术部位,以检查感染迹象.
主要成果:
- 整体SSI率为4.5% (9/197名患者).
- 感染率:对照组的3.5% (7/197) 与局部 gentamicin 组的1% (2/197).
- 群体之间的SSI率没有统计学上显著的差异.
- 四名患者 (2.0%) 患有血瘤,3名患者也患有SSI.
结论:
- 局部 Gentamicin 在网修复后的早期 SSI 预防方面没有显著的益处.
- 结果表明,目前的做法可能不会通过常规的局部 gentamicin 使用来改善.
- 可能需要进一步的研究来探索替代性SSI预防策略.
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