为儿童和成人急性和慢性疼痛扩展现实试验开发核心结果集:德尔菲共识建设过程
Courtney W Hess1, Deirdre E Logan2,3, Brittany N Rosenbloom4,5
1Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
Journal of medical Internet research
|May 23, 2025
概括
建立了扩展现实 (XR) 疼痛试验的核心结果,包括疼痛严重程度,不良事件,用户体验和心理构造. 这标准化了儿童和成人急性和慢性疼痛干预措施的评估.
科学领域:
- 疼痛管理 疼痛管理
- 扩展现实 (XR) 干预 干预
- 临床试验方法论 临床试验方法论
背景情况:
- 高质量的试验和结果评估对于促进急性和慢性疼痛治疗至关重要.
- 扩展现实 (XR),包括虚拟和增强现实,已经成为一种重要的非药物治疗疼痛.
- 对XR疼痛干预措施缺乏标准化的结果评估策略,阻碍了研究进展.
研究的目的:
- 为临床试验推一套标准化的核心结果,涉及儿童和成人急性和慢性疼痛的XR干预.
- 建立关于基本结果领域的共识,以提高XR疼痛研究的质量和可比性.
主要方法:
- 采用多阶段方法,首先对XR疼痛试验进行系统审查,以确定常见的评估结果领域.
- 一项德尔菲调查对临床医生和研究人员进行,他们积极参与XR治疗疼痛.
- 通过面对面的会议和随后的Delphi调查轮,达成共识,遵守风湿病学指导方针的结果措施.
主要成果:
- 系统性审查包括90个儿科和104个成人XR疼痛研究.
- 通常测量的结果包括疼痛强度,分心,焦虑,满意度和不良事件.
- 所有XR疼痛试验的强制性领域是疼痛严重程度,不良事件,用户体验和心理结构;对于慢性疼痛来说,疼痛干扰是强制性的.
结论:
- 建立一个核心结果集对于加强XR干预在疼痛管理中的证据基础至关重要.
- 这一核心集将提高跨儿科和成人群体的研究结果的一致性和有效性.
- 未来的工作重点是为每个已确定的结果领域推验证的措施.
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