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Updated: Jan 18, 2026

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19名患有小纤维神经病变的患者的微神经图像:试点研究

Andrea Beisswanger1, Greta Z Peschke2, Noortje W M V D Braak2

  • 1Research Group Neuroscience, Interdisciplinary Centre for Clinical Research Within the Uniklinik RWTH Aachen University, Aachen, Germany.

Pain
|May 23, 2025
PubMed
概括

小纤维神经病变 (SFN) 涉及导致疼痛的C纤维功能障碍. 微神经图识别了过度活跃的C-nociceptors作为SFN患者持续神经病痛的潜在生物标志物.

关键词:
微神经图谱是一种微神经图谱.神经病变性疼痛 神经病变性疼痛音感受体生理学 音感受体生理学小纤维神经病变 小纤维神经病变

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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