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对于医疗控制和不受控制的白内障初级开放角度视光眼的法哥尼切除术的结果:一个多中心研究
Yunhe Song1, Xiangxiang Ye2, Mingmin Yang3
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases.
Journal of glaucoma
|May 23, 2025
概括
角膜切除术 (phacogoniotomy) 结合了乳化,眼内透镜植入和角膜切除术,有效地治疗具有白内障的初级开角玻璃眼 (POAG). 这种安全的程序显著降低了医疗控制和不受控制的POAG患者的眼内压力和药物依赖.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 白内障手术 手术 白内障手术
背景情况:
- 主要开角青光眼 (POAG) 与共存的白内障构成了外科手术的挑战.
- 目前的治疗方法往往涉及多种程序或药物,有效性各不相同.
- 发管切除术提供了一种结合的方法,可以同时解决这两种情况.
研究的目的:
- 为了评估法哥尼切除术 (法可乳化,眼内镜片植入,以及120度法哥尼切除术) 对白内障的POAG的疗效和安全性.
- 评估在医疗控制和不受控制的POAG患者中程序的结果.
主要方法:
- 一项多中心观察研究,涉及100名参与者 (132只眼睛) 患有POAG和白内障.
- 患者在基线被分为医疗控制 (IOP ≤21 mmHg) 或不受控制 (IOP>21 mmHg) 的患者.
- 进行了至少12个月的随访,记录眼内压力 (IOP),药物使用,并发症和视力敏度.
主要成果:
- 平均内血压从手术后的21.2±7.4 mmHg下降到14.7±2.9 mmHg (P <0.05).
- 低血压药物的平均数量从1.6±1.2减少到0.3±0.6.
- 在81.8%的眼睛中取得了完全的手术成功,在89.4%的眼睛中取得了合格的成功,严重并发症的发生率很低.
结论:
- 角切除术是一种有效和安全的手术治疗,用于治疗白内障的原发性开角绿内障.
- 该程序显示显著降低IOP和减少药物依赖.
- 无论患者的POAG.医疗控制状态如何,结果都是有利的.
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