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Updated: Jan 18, 2026

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与精神分裂症相关的突触功能障碍和Akap11缺陷小鼠中的异常感官运动门.

Ya-Qi Zhang1,2,3, Xin Cai1,2, Qing Zhang4,5

  • 1State Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.

Schizophrenia bulletin
|May 23, 2025
PubMed
概括

在小鼠中,Akap11缺乏会导致与精神分裂症相关的突触和行为缺陷. 这项研究强调AKAP11是精神分裂症的显著风险基因,其中涉及突触功能障碍在其发病过程中.

关键词:
在 AKAP11 里面,你会看到.树状的棘 树状的棘突触 (Synapses) 是一个突触的组成部分.类似焦虑的行为.前脉冲抑制的抑制.精神分裂症是一种精神分裂症.

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