结直肠线炎病例系列:一个不常见的实体
Pablo Del Val-Ruíz1, Daniel Fernández-Martínez2, Beatriz Carrasco-Aguilera1
1Unit of Coloproctology, Department of General and Digestive Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
直肠的塑性线性炎 (LP) 是一种罕见的疾病,具有非特异性症状. 由于微妙的内镜发现和不确定的活检,诊断具有挑战性,尽管化疗,但往往导致预后不佳.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 塑性线膜炎 (LP) 是一种罕见的疾病,涉及恶性细胞扩散透到空心器官的粘膜下和肌肉自身层.
- 肠直肠LP由于其罕见性和非特异性临床表现而特别存在诊断挑战.
研究的目的:
- 突出诊断挑战和与直肠线膜炎塑性相关的不良预后.
- 审查临床表现,诊断方式和直肠LP的管理.
主要方法:
- 一系列病例涉及三名患有直肠塑性线性炎的患者.
- 诊断程序包括结肠镜检查,CT检查,MRI检查,以及组织病理学/免疫组织化学分析.
- 治疗包括化疗,并为并发症预留了手术.
主要成果:
- 结肠镜检查显示直肠狭窄,粘膜保留;成像显示直肠周围壁加厚.
- 组织病理学证实了恶性细胞透到粘膜下.
- 所有患者都接受了化疗,但经历了疾病进展,表明预后不佳.
结论:
- 直肠LP表现出非特异性症状和特征性内镜/成像发现的子粘膜厚.
- 确定的诊断需要组织学,但活检可以是非诊断的.
- 晚期诊断和有限的治疗选择导致预后不佳,化疗是主要治疗方法.
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