人类近红外时空色彩视觉由上转换式隐形眼镜实现
Yuqian Ma1, Yunuo Chen1, Sheng Wang2
1Department of Ophthalmology, The First Affiliated Hospital of USTC, Hefei National Research Center for Physical Sciences at the Microscale, New Cornerstone Science Laboratory, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China; State Key Laboratory of Eye Health, Institute of Advanced Technology, University of Science and Technology of China, Hefei 230026, China.
Cell
|May 23, 2025
概括
研究人员开发了可穿戴的近红外 (NIR) 上转换隐形眼镜 (UCL),使人类能够看到无形的NIR光. 这些镜头能够感知NIR时间,空间和颜色信息,扩展人类的视觉感知.
科学领域:
- 生物医学工程
- 材料科学
- 光学学
背景情况:
- 人类的视力仅限于可见光谱.
- 对于各种应用,感知近红外 (NIR) 无形光线是可取的.
- 目前用于NIR检测的方法通常是侵入性的或复杂的.
研究的目的:
- 开发可穿戴的近红外视觉隐形眼镜.
- 使人类能够感知NIR光谱中的时间,空间和颜色信息.
- 制造具有生物相容性和光学适用的升级式隐形眼镜 (UCL).
主要方法:
- 可穿戴近红外 (NIR) 上转换式隐形眼镜 (UCL) 的制造.
- 在小鼠中测试NIR感知和行为决策.
- 对人类进行试验,以评估NIR时间和空间信息的区分能力.
- 用于NIR色视的三色UCL (tUCL) 的开发.
主要成果:
- 戴着UCL的小鼠能够识别NIR信息并做出决定.
- 穿着UCL的人类参与者可以区分NIR时间编码和空间图像.
- 三色UCL (tUCL) 能够将多个NIR光谱区分为主色.
- 实现了人类的NIR时空色彩视觉.
结论:
- 可穿戴的聚合物材料为非侵入性NIR视觉提供了途径.
- 通过启用NIR光感知,UCL显著扩大了人类的感觉能力.
- 这项技术在需要增强视觉感知的各个领域都有潜在的应用.
相关概念视频
Color Vision
740
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
740
Photoreceptors and Visual Pathways
6.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.5K
Anatomy of the Eyeball
7.6K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.6K
Vision
55.4K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
55.4K
The Retina
70.7K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
70.7K
Channel Rhodopsins
2.6K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
2.6K


