在不确定的胆管狭窄症中,胆管镜导向的咬咬 (-咬咬) 活检的价值
David M de Jong1, Pieter Jan F de Jonge1, Pauline M C Stassen1
1Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Endoscopy
|May 23, 2025
概括
咬对咬活检 (BBB) 与数字单操作员胆管镜检 (dSOC) 中的标准单次活检相比,对无限期胆道狭窄 (IBDS) 的诊断准确度没有提高. 之前的干预措施,如支架安置,降低了诊断产量.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 肝胆道医学 肝胆道医学
背景情况:
- 数字单操作者胆管透镜 (dSOC) 通过向活检增强了不确定的胆道狭窄 (IBDS) 的诊断.
- 在dSOC期间IBDS的最佳活检技术仍未确定.
研究的目的:
- 在接受dSOC的IBDS患者中,比较单次活检与咬对咬活检 (BBB) 的诊断准确性.
- 评估影响诊断产量的因素,包括先前的干预措施.
主要方法:
- 一项国际,多中心,前性研究包括了89名接受dSOC的IBDS患者.
- 所有患者都接受了至少四次单一活检和一个BBB.
- 通过病理学和1年的随访证实了诊断;这两种技术的准确性是主要结果.
主要成果:
- 单次活检的技术成功率为92.1%,BBB.的技术成功率为87.6%.
- 恶性病症在62.2%的患者中得到证实,随着完整的随访.
- 对于这两种技术,恶性瘤/高度形的诊断准确性相似 (78.8%单一 vs 77.6% BBB);之前的支架放置或ERCP组织获取降低了产量.
结论:
- 咬对咬活检 (BBB) 与不确定胆道狭窄症 (IBDS) 至少四次单次活检相比没有更高的诊断准确性.
- 在ERCP期间先前的干预措施,如支架安置或组织采集,显著降低了dSOC活检的诊断产量.
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