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Updated: Jan 31, 2026

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针对AML细胞药物耐药性的动态异质性主要是由多奥米克分析揭示的表观遗传学机制驱动的

Yulong Zhang1, Yanfang Lu2, Liyao Mai3

  • 1Department of Biochemistry and Molecular Biology, and Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, School of Basic Medical Sciences, Guangzhou, Guangdong, China; Precision Regenerative Medicine Research Centre, Medical Science Division, and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao 999078, China.

Journal of advanced research
|May 23, 2025
PubMed
概括

急性髓性白血病 (AML) 耐药性主要是由表观基因组变化驱动的,而不是基因突变. 了解这些细胞和分子机制是开发这种侵袭性癌症新疗法的关键.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.药物耐药性 药物耐药性 药物耐药性多个omics的多个omics.样本多重复合的使用方法单细胞测序是一种单细胞测序.

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