世界贸易中心职业队伍在纵向监控中的螺旋计图案过渡
Jonathan Weber1, Zitong Zhang2, John T Doucette2
1DeMatteis Cardiovascular Institute, St. Francis Hospital & Heart Center, Roslyn, NY, USA.
世界贸易中心 (WTC) 的应急人员经常患上慢性下呼吸道疾病. 较高的WTC暴露和BMI预测过渡到低强迫生命能力 (FVC),一个稳定的状态,而阻塞不太常见.
科学领域:
- 肺部医学 肺部医学
- 环境健康 环境健康
- 流行病学 流行病学
背景情况:
- 世界贸易中心 (WTC) 灾难救援人员表现出各种慢性下呼吸道疾病.
- 纵向监测显示了这个群体中可变的螺旋计图案.
- 了解疾病进展和风险因素对于暴露在WTC的人来说至关重要.
研究的目的:
- 系统地检查WTC响应者中的螺旋计模式转换.
- 评估身体质量指数 (BMI) 和WTC暴露强度与这些转变的关联.
- 为了确定WTC暴露后慢性呼吸道疾病发展的预测因素.
主要方法:
- 分析了来自10810名西奈山世界贸易中心 (WTC) 应急人员队伍成员的螺旋测量数据.
- 三种螺旋计图案的定义:正常,阻塞和低强迫生命能力 (FVC).
- 应用多态马尔科夫式模型来分析随时间的模式转换.
主要成果:
- 低FVC是WTC工人中最常见的异常螺旋测量模式.
- 较高的WTC曝光强度和增加的BMI是过渡到低FVC的重要预测因素.
- 与低FVC相比,向阻塞性模式的过渡很少发生,并且表现出更大的不稳定性.
结论:
- 低FVC是WTC响应者中相对稳定的螺旋测量模式.
- WTC暴露强度和BMI独立地与低FVC的发展有关.
- 这些发现强调了WTC暴露对呼吸系统健康的长期影响,以及个人因素 (如BMI) 的作用.
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