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抑制GRP75可以减轻动脉化

Jonas Heyn1, Andrea Gorgels1, Nicolas Hense1

  • 1Department of Internal Medicine I - Cardiology, Medical Faculty, Uniklinik RWTH Aachen, RWTH Aachen University, 52074, Aachen, Germany.

Atherosclerosis
|May 23, 2025
PubMed
概括

葡萄糖调节蛋白75 (GRP75) 连接了血管光滑肌细胞 (SMC) 中的线粒体和内质网膜 (ER). 抑制GRP75通过改善线粒体功能和减少ER压力来减少动脉化.

关键词:
动脉的化 动脉的化细胞外囊泡中的细胞外囊泡.线粒体-ER接触方式线粒体相关的膜.血管光滑肌细胞是血管光滑肌细胞.

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