老龄化如何影响皮质动力学和双重任务转过程中的步态,由fNIRS揭示
GeroScience
|May 23, 2025
概括
与年轻人相比,老年人在认知转向的双重任务中表现出大脑活动的改变和步伐长度的减少. 增强的大脑功能连接可能会改善老年人的双重任务性能,帮助预防跌倒.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 生物力学 生物力学
背景情况:
- 衰老影响神经运动控制,影响步态和认知功能.
- 双重任务对老年人来说比年轻人更具挑战性,增加了跌倒的风险.
- 了解复杂任务期间大脑激活的年龄相关差异至关重要.
研究的目的:
- 在认知转向双重任务期间,比较年轻人与老年人的皮质激活和步行表现.
- 在双重任务行走期间,研究大脑功能连接的年龄相关差异.
- 确定老年人双重任务缺陷背后的神经机制.
主要方法:
- 功能近红外光谱学 (fNIRS) 测量皮质激活.
- 三维运动捕捉分析了步态参数.
- 参与者执行单任务和双任务 (认知转向步行) 条件.
主要成果:
- 年轻的成年人在双重任务中表现出皮质激活的增加,与老年人不同.
- 年长的成年人表现出脚步长度下降和特定大脑区域的功能连接性增加.
- 在双重任务中,皮层激活在年轻人中明显高于老年人.
结论:
- 与年轻人相比,老年人在认知转向双重任务期间表现出明显的神经运动适应.
- 改变的大脑调制机制有助于较差的双重任务性能和增加老年人跌倒的风险.
- 增强大脑功能连接的策略可以提高双重任务的性能,并减少老年人群中跌倒风险.
相关概念视频
The Effect of Aging on Tissues
3.6K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.6K
Bone Disorders
8.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.0K
Alterations in Muscle Tone lll
29
Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
29


