耳子亚型与精神疾病之间的双向关联
Daniel Karasik1,2, Rishi Katragadda2, Christopher Wen3
1Department of Otolaryngology - Head and Neck Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
The Laryngoscope
|May 24, 2025
概括
非脉动性耳声 (NPT) 显著增加了发展泛性焦虑症 (GAD) 和严重抑郁症 (MD) 的风险. 脉动性耳 (PT) 患者与这些精神疾病有双向联系,这表明综合心理健康护理至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 耳是一种常见的听觉感知,有不同的亚型,包括脉动性耳 (PT) 和非脉动性耳 (NPT).
- 精神疾病如通用焦虑症 (GAD) 和严重抑郁症 (MD) 经常与耳并发,但亚型特定的关系尚不清楚.
研究的目的:
- 调查声亚型 (PT和NPT) 与GAD和MD的发展之间的时间和双向关联.
- 为了比较与PT与NPT相关的精神疾病负担.
主要方法:
- 使用TrinetX研究网络数据的回顾性队列研究 (超过1.4亿患者).
- 根据PT,NPT,GAD和MD的ICD-10代码分类的患者.
- 倾向性得分匹配 (PSM) 用于控制混因素;统计分析包括95%置信区间 (CI) 的几率比率 (OR).
主要成果:
- 与脉动性耳 (PT) 患者相比,非脉动性耳 (NPT) 患者患上GAD和MD的风险明显更高.
- 在PT患者中,即使在接受治疗/未接受治疗的子组中,患上GAD和MD的风险也始终较低.
- 在耳患者中,那些先前患有GAD或MD的人更有可能患有PT而不是NPT.
结论:
- NPT与患上GAD和MD的风险更高有关,这表明精神疾病负担更高.
- 在PT和先前存在的GAD/MD之间存在双向关系.
- 调查结果强调将心理健康评估纳入耳声护理,并制定特定亚型的管理策略.
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