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Updated: Sep 20, 2025

Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland
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CRL7FBXW8综合控制乳腺干细胞通过调节NUMB水平来控制乳腺干细胞区间

Simone Sabbioni1, Maria Grazia Filippone1,2, Letizia Amadori1

  • 1IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|May 24, 2025
PubMed
概括

由于过度降解,乳腺癌 (BC) 中常见的是瘤抑制剂NUMB蛋白功能的丧失. 抑制CRL7FBXW8复合物恢复NUMB水平,并对抗BC的进展.

关键词:
CRL7FBXW8 复杂的复合体在 NUMB NUMB 里面,你会看到一个数字.乳腺癌 乳腺癌 乳腺癌癌症干细胞是癌症干细胞.蛋白质群体的降解

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