结肠直肠和直肠双内镜检查,以评估性结肠炎的内镜和组织学缓解:一项前性研究
Clara Yzet1, Capucine Moreau1, Denis Chatelain2
1Gastroenterology Unit, Amiens University Hospital, Amiens, France.
直肠检查准确地检测到性结肠炎 (UC) 患者的全结肠缓解. 仅靠直肠的检测结果就足以监测UC,为评估内镜和组织学愈合提供了直肠肌样镜的替代方案.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠道疾病研究研究
- 临床内镜检查 临床内镜检查
背景情况:
- 性结肠炎 (UC) 治疗越来越多地针对内镜和组织学缓解.
- 左结肠和直肠检测结果的准确性用于检测全结肠缓解并未得到充分确立.
研究的目的:
- 为了比较直视显微镜 (RS) 和直视镜的诊断准确度,以检测UC患者整个结肠中的内镜和组织学愈合.
主要方法:
- 未来包括接受结肠镜检查的UC患者.
- 内镜治疗定义为梅奥内镜评分 (MES) = 0;组织学治疗作为南希指数 ≤ 1.
- 使用科恩的卡帕系数评估结肠镜,RS和直肠镜之间的协议.
主要成果:
- 结肠镜和RS/直肠镜之间对于内镜和组织学愈合的高度一致 (kappa ≈ 0.830.95).
- 直肠镜显示与结肠镜几乎完全一致 (内镜的kappa = 0.83,组织学愈合的0.80)
结论:
- 结直肠内镜和组织学发现准确地预测UC患者的全结肠缓解.
- 直肠检查可以作为监测UC患者RS的可行的替代方案.
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