艾滋病毒感染者的内脏和皮肤莱什曼病
Nicolas Laverde-Sudupe1, Angela Lizeth Giraldo-Serna1, Mariana Vasquez-Amaya2
1Pontificia Universidad Javeriana de Cali, Cali, Colombia.
International journal of STD & AIDS
|May 24, 2025
概括
这份病例报告详细介绍了一名患有晚期艾滋病毒/艾滋病的患者,他同时出现了内脏和粘膜皮肤莱什曼病. 通过骨髓检查证实了诊断,突出显示了免疫功能低下个体的非典型Leishmaniasis表现.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 寄生虫学的寄生虫学
背景情况:
- 莱什曼病是晚期艾滋病毒/艾滋病患者的重大机会性感染.
- 典型的呈现包括皮肤,粘膜皮肤和内脏形式.
- 非典型的表现可能会带来诊断挑战,特别是在免疫功能低下的患者中.
研究的目的:
- 报告患有晚期艾滋病毒/艾滋病的患者同时患有内脏和粘膜皮肤莱什曼病的病例.
- 突出莱什曼病的非典型表现所带来的诊断挑战.
- 强调考虑艾滋病毒/艾滋病患者患有不明原因症状的机会性感染的重要性.
主要方法:
- 一份病例报告显示,一名24岁的男性患有先进的艾滋病毒/艾滋病 (CD4+数量为3个细胞/毫米3).
- 临床表现包括神经系统恶化,非典型的生殖器和全细胞减小.
- 通过骨髓检查证实了诊断,骨髓检查显示了Leishmania* amastigotes.
主要成果:
- 该患者同时出现了内脏和粘膜皮肤莱什曼病,这是一个非典型的表现.
- 骨髓检查对于识别 *Leishmania* amastigotes至关重要.
- 用脂质体安福特乙和密尔特福辛治疗导致临床改善.
结论:
- 莱什曼病的非典型表现需要在艾滋病毒/艾滋病患者中高度怀疑指数.
- 骨髓检查对于诊断扩散式莱什曼病来说至关重要.
- 迅速的多种药物治疗对于管理免疫受损个体的复杂共感染至关重要.
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