内逆流与随后的脏痕有关:一项回顾性研究
Jisun Hwang1, Su Jin Lee2, Ki Soo Pai3,4
1Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
Pediatric nephrology (Berlin, Germany)
|May 24, 2025
概括
内逆流是一种皮叶管管逆流,在患有尿路感染 (UTI) 的儿童中显著增加脏痕的风险. 这一发现有助于为患有尿路感染和膀回流症 (VUR) 的儿童提供量身定制的治疗.
科学领域:
- 儿科脏病学 儿科脏病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 诊断成像 诊断成像 诊断成像
背景情况:
- 儿童的尿路感染 (UTI) 可能导致脏痕.
- 内逆流 (pyelotubular回流) 是尿液回流到脏的特定模式.
- 内反流和脏痕之间的联系需要进一步调查.
研究的目的:
- 为了确定内反流是否与被诊断患有尿路感染的儿童的脏痕有关.
- 评估内逆流作为性痕的独立预测因素.
主要方法:
- 对441名患有尿路感染的儿童进行了回顾性审查,这些儿童接受了排空囊透视图 (VCUG) 和技术-99m二聚糖酸 (DMSA) 扫描.
- 在VCUG上发现了内逆流;通过DMSA扫描评估了脏痕.
- 多变量逻辑回归分析,调整为膀外流 (VUR) 等级和临床变量.
主要成果:
- 内逆流存在于13.7%的脏单位与VUR.
- 内逆流与脏痕的风险增加显著相关 (OR 3.35).
- 92%的DMSA扫描缺陷在单位内反流局部化到反流部位.
结论:
- 内逆流是患有尿路感染的儿童脏痕的独立预测因素,超出了标准VUR分级.
- 在VUR评估期间识别内反流是非常重要的.
- 这一发现支持为儿科UTI和VUR开发个性化管理策略.
相关概念视频
Acute Kidney Injury II: Pathophysiology
101
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
101
Acute Kidney Injury III: Clinical Manifestations
108
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
108
Acute Kidney Injury IV: Diagnostic Studies and Prevention
64
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
64
Acute Kidney Injury I: Introduction
85
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
85
Kidney Transplant II: Surgical Procedure
78
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
78
Chronic Kidney Disease I: Introduction
84
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
84


