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65岁及以上成年人中的维生素矿物质补充剂和认知:多项基于人口的横截面研究

Daniela Marques¹, Martin Preisig², Pedro Marques-Vidal³

¹University of Lausanne, Lausanne, Switzerland.

European journal of nutrition

|May 24, 2025

概括

维生素-矿物质补充剂 (VMS) 与老年人的认知表现没有显著的关联. 这项研究没有发现VMS在维持或增强认知方面具有临床意义的益处.

科学领域:

老年学是一门学科.
营养神经科学营养神经科学
认知老龄化认知老龄化

背景情况:

许多老年人服用维生素矿物质补充剂 (VMS),旨在防止认知能力下降或提高认知功能.
在老年人群中,VMS对认知表现的实际影响仍然是研究的关键领域.

研究的目的:

调查65岁及以上个体定期摄入维生素矿物质补充剂 (VMS) 与认知表现之间的关联.
为了确定VMS消费是否与更好的认知功能或更慢的认知衰退率有关.

主要方法:

该研究使用了基于人口的Collaus RainbowPsyColaus队列的数据,包括三个后续评估.
65岁及以上的参与者被分为VMS消费者和非消费者.
用一系列测试来评估认知功能,包括MMSE,Stroop,CERAD,流利性任务以及格罗伯和巴斯克记忆测试.

主要成果:

在对多个变量进行调整后,在大多数认知测试中,在VMS非消费者和消费者之间没有观察到认知表现的显著差异.
在Stroop C测试和Grober和Buschke情节性记忆测试中发现了微小的统计学上显著的差异,但这些被认为在临床上无关紧要.
具体发现包括Stroop C的非消费者略有更好的表现,以及VMS消费者在Grober和Buschke测试中的自由和有线回忆中的混合结果,没有明确的整体认知优势.

结论:

该研究得出结论,使用维生素矿物质补充剂与老年人认知表现之间没有临床显著的关联.
研究结果表明,VMS可能不会为这一群体的认知健康带来实质性的好处.
进一步的研究可以探索特定的VMS配方或亚群,但目前的证据表明缺乏广泛的认知增强.

关键词:

认知认知是一种认知.横截面研究横截面研究老年人,年长的人.维生素补充剂维生素补充剂

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