接受体外受精的妇女的针治疗:更新的系统性审查和元分析,并进行试验顺序分析
Qin-Wei Fu1, Shao-Mi Zhu2, Ji Chen3
1Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China; Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Hamilton L8S 4L8, Canada.
International journal of nursing studies
|May 24, 2025
概括
针可以提高体外受精 (IVF) 的成功率,并减少疼痛和焦虑. 然而,它与更高的早期流产风险有关,需要进一步调查.
科学领域:
- 生殖医学 生殖医学
- 补充和替代医学 补充和替代医学
- 基于证据的医学基于证据的医学.
背景情况:
- 在体外受精 (IVF) 的成功率低于最佳.
- 针作为IVF的补充疗法正在被探索.
- 针旨在改善生殖结果,减少疼痛/焦虑.
研究的目的:
- 评估针在IVF中的有效性和安全性.
- 评估对生殖结果 (妊娠率) 的影响.
- 检查疼痛减轻和焦虑缓解.
主要方法:
- 42项试验 (7400名参与者) 的系统审查和元分析.
- 针 (手动/电动) 与假/空白控制相比较.
- 利用了柯克兰方法,试验顺序,元回归和偏差分析.
主要成果:
- 针显著改善了生化 (RR=1.28) 和临床怀孕率 (RR=1.19).
- 与更好的疼痛管理和减少焦虑有关.
- 增加了早期流产率 (RR=1.51);注意到轻度不良事件.
结论:
- 针可以改善试管婴儿的生殖结果,疼痛和焦虑.
- 潜在的早期流产风险增加需要谨慎.
- 需要进一步严格的试验来验证发现.
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