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Updated: Sep 20, 2025

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein GST-RhoAG17A from Epithelial Cell Lysates
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氨酸核酸交换因子EPAC1中的SUMO相互作用动机对于亚细胞向和功能是必需的

Wenli Yang1, Fang Mei1, Wei Lin1

  • 1Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, USA; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center, Houston, Texas, USA.

The Journal of biological chemistry
|May 24, 2025
PubMed
概括

EPAC1中的SUMO相互作用基因 (SIM) 对其与核孔综合体的相互作用和cAMP信号的调节至关重要. 破坏SIM影响EPAC1影响

关键词:
这是RanBP2/Nup3588.这就是SUMOylation的作用.在CAMP中,我们可以使用cAMP.核包裹是一个核包裹.核孔复合体是核孔复合体.

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