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Updated: Sep 20, 2025

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
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Published on: March 10, 2023

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中核结合因子的二次突变和细胞遗传改变 - 急性髓性白血病 (CBF-AML):系统性审查和元分析

Amin Javidan1, Alireza Azarboo1, Sayeh Jalali1

  • 1School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Critical reviews in oncology/hematology
|May 24, 2025
PubMed
概括

核心结合因子急性髓性白血病 (CBF-AML) 的二次遗传变化显著影响患者的存活率. 在c-KIT和FLT3-ITD的突变,以及三症8,与较差的结果有关,强调在治疗决策中需要基因分析.

关键词:
在C-Kit中发生突变.核心结合因子急性髓性白血病 (CBF-AML)细胞遗传异常 细胞遗传异常在FLT3突变中.进行元分析分析.

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