在预期姿势调整的运动准备过程中,背侧前额叶皮层的作用
Jiajia Yang1, Guifang Zhang1, Xiaoyu Gao1
1Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Zhongshan Road 2, Guangzhou, 510080, China.
Brain topography
|May 24, 2025
概括
在运动准备过程中,在背侧前额叶皮层 (DLPFC) 上进行重复性横磁刺激 (rTMS) 提高了初级运动皮层 (M1) 中的神经效率. 这种调制有助于将预期姿势调整 (APA) 与自愿运动相结合.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 认知神经科学 认知神经科学
背景情况:
- 预期姿势调整 (APA) 对于步行启动至关重要,可能受到背侧前额皮层 (DLPFC) 血液动力学反应的影响.
- 在发动机准备过程中,DLPFC在调节APA集成中的确切作用尚不清楚.
研究的目的:
- 为了研究运动准备期间左侧DLPFC的重复性横磁刺激 (rTMS) 如何影响神经活动和APAs.
- 阐明初级运动皮层 (M1) 在DLPFC和APAs之间的关联中扮演的调解角色.
主要方法:
- 17名参与者在快速举臂任务中,在左侧DLPFC上进行了真实和假的rTMS.
- 功能近红外谱学 (fNIRS) 测量了DLPFC,补充电机区域 (SMA) 和M1激活.
- 表面电肌图 (sEMG) 评估了腰部多体中的APA延迟和振幅.
主要成果:
- 与假刺激相比,真正的rTMS显著降低了DLPFC,SMA和M1激活.
- rTMS减少了腰部多管中的APA延迟和幅度.
- DLPFC的激活与M1和SMA的激活呈正相关性,M1调解了DLPFC与APA的关联.
结论:
- 在运动准备期间通过DLPFC进行rTMS可以提高M1的神经效率.
- 这种增强方便了APA与自愿运动的整合,建议DLPFC-M1通道用于运动控制.
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