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扩大静脉血栓栓塞的差异 胰腺癌手术后的预防
Kelly Dong1,2, Ashlynn Fuccello3, Mario Schootman3
1Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Annals of surgical oncology
|May 24, 2025
概括
在胰腺癌手术后,对延长静脉血栓塞栓症 (VTE) 预防的坚持是低的,但在增加. 静脉瘤预防的差异与患者的人口结构和医疗保健因素有关.
科学领域:
- 在瘤学瘤学.
- 血管外科 血管外科
- 医疗保健服务研究 医疗服务研究
背景情况:
- 目前的指导方针建议在胰腺癌手术后进行为期4周的延长静脉血栓栓塞 (VTE) 预防.
- 在临床实践中,遵守这些VTE预防指南的程度仍然非常低.
研究的目的:
- 分析趋势并确定与胰腺癌手术后延长VTE预防的处方相关的因素.
- 了解符合条件的患者在接受VTE预防方面的差异.
主要方法:
- 对接受手术的胰腺癌患者的SEER-Medicare数据集 (2007-2020) 的回顾性分析.
- 利用多变量逻辑回归来确定延长VTE预防处方的预测因素.
- 主要结局:处方填充在出院后5天内.
主要成果:
- 在4827名符合条件的患者中,只有9.7%接受了延长的静脉瘤预防,主要是以诺沙巴林为主.
- 处方率显著增加,从0.4% (2008) 增加到23.1% (2019).
- 年轻的年龄,白人种族,农村,胰腺二切除术,更高的医院容量,外科瘤学家专业和晚期手术期与增加的预防接收有关.
结论:
- 胰腺癌手术后的延长VTE预防处方正在增加,但仍然适度.
- 静脉瘤预防的差异是多因素的,受人口和医疗保健相关因素的影响.
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