脊椎动物的品种本体学:朝着有效的品种数据标准化
Kathleen R Mullen1, Imke Tammen2, Nicolas A Matentzoglu3
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Journal of veterinary internal medicine
|May 25, 2025
概括
脊椎动物品种本体学 (VBO) 标准化了兽医品种名称,改善了数据共享,并为精准医学提供了先进的分析. 这种开放的,社区驱动的资源增强了兽医数据的互操作性和可计算性.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 生物信息学是一种生物信息学.
- 本体论发展发展 本体论发展
背景情况:
- 在兽医领域缺乏通用数据标准,阻碍了互操作性和数据集成.
- 这种局限性阻碍了诊断,治疗和精准医学的进步.
研究的目的:
- 建立一个基于逻辑的标准,用于记录脊椎动物品种名称.
- 通过统一的品种命名法,改善兽医和比较医学中的数据利用.
主要方法:
- 使用来自全球组织,注册表和专家的数据开发了脊椎动物品种本体学 (VBO).
- 采用手动和计算方法来编制品种信息和元数据.
- 使用AI兼容性描述逻辑进行分类的VBO术语.
主要成果:
- VBO包括49个物种的超过19500个牲畜和伴侣动物品种概念.
- 品种是根据社区/专家公约进行分类的,并与NCBI分类学联系在一起.
- VBO元数据包括同义词,标识符和交叉引用,支持高级分析.
结论:
- 采用VBO作为标准提高了兽医数据的互操作性和可计算性.
- 促进在兽医健康记录中应用基于信息的精准医学工具.
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