对于EGFR突变非小细胞肺癌的新疗法在osimertinib时代的新疗法

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Updated: Sep 20, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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Jaime Rubio-Perez1, Roberto Hernandez2, Carlota Santolaya3

  • 1Memorial Sloan Kettering Cancer Center, NY, USA; Department of Medical Oncology, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain.

Cancer treatment and research communications
|May 25, 2025
PubMed
概括

同突变,特别是TP53,显著恶化了EGFR突变非小细胞肺癌 (NSCLC) 患者的治疗结果. 识别这些变化对于开发向治疗和改善患者预后至关重要.

关键词:
在EGFR突变的NSCLC中.没有NGS,没有NGS.TKI 阻力 阻力 的 TKI 阻力.有TP53突变的突变.有针对性的治疗.

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