饮食模式和从正常认知过渡到轻度认知障碍及其逆转:对老年人的纵向研究
Xiaofu Du1, Bin Gao2, Jiangtao Zhang3
1Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China.
Clinical nutrition (Edinburgh, Scotland)
|May 25, 2025
概括
某些饮食模式,如健康植物性饮食指数 (hPDI) 和简化健康饮食指数 (SHEI),可能有助于轻度认知障碍 (MCI) 的老年人恢复正常认知 (NC). 这些饮食似乎也减缓了认知能力的下降.
科学领域:
- 老年学是一门学科.
- 营养神经科学 营养神经科学
- 认知老龄化 认知老龄化
背景情况:
- 与进展为痴呆症相比,轻度认知障碍 (MCI) 到正常认知 (NC) 逆转的研究不足.
- 了解影响老年人认知转变的因素对于公共卫生至关重要.
研究的目的:
- 为了确定老年人中MCI到NC逆转的速度.
- 研究特定饮食模式与认知状态转变之间的关联.
主要方法:
- 分析了来自11211名65岁以上的成年人的纵向数据.
- 评估四种饮食模式:植物性饮食指数 (PDI),简化健康饮食指数 (SHEI),饮食多样性得分 (DDS) 和地中海-DASH神经退行性延迟干预 (MIND).
- 应用多态马尔科夫模型来估计认知过渡率和饮食模式关联.
主要成果:
- MCI到NC的逆转率为9.4%.
- 健康的PDI (hPDI),SHEI,DDS和MIND饮食模式与从正常认知 (NC) 进展到MCI的风险降低有关.
- 对HPDI和SHEI的更高遵守与从MCI返回NC的可能性增加有关.
结论:
- 包括hPDI,SHEI,DDS和MIND在内的饮食模式可能会降低从NC到MCI认知能力下降的风险.
- 在老年人中,hPDI和SHEI与从MCI回归到NC的认知回归的可能性更大.
- 需要进一步的干预研究来验证这些饮食模式的发现.
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