相关实验视频
Updated: Sep 20, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
由扩展光谱β-乳糖酶和AMPC生产生物体引起的急性胆道炎的危险因素
Takuro Nishiwaki1,2, Shigenobu Yoshimura1, Naoto Hosokawa3
1Department of Gastroenterology, Kameda Medical Center, Kamogawa, Japan.
急性胆道炎 (AC) 中耐药细菌的危险因素包括先前使用抗生素,透析和扩展光谱β-乳糖酶产生肠杆菌 (ESBL-E) 的养老院住宿. 染色体介导的AMpC产生的肠杆菌 (CAE) 的危险因素包括先前的抗生素使用和内镜缩切除病史.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 微生物学 微生物学
背景情况:
- 及时服用抗生素对于急性胆炎 (AC) 管理至关重要.
- 选择抗生素需要考虑严重程度和耐药性模式,特别是扩展光谱β-乳糖酶产生肠杆菌 (ESBL-E) 和染色体介导的AMPC产生肠杆菌 (CAE).
- 影响AC抗性的患者特征尚不清楚.
研究的目的:
- 在AC患者中确定与ESBL-E和CAE相关的风险因素.
主要方法:
- 在日本一家三级医疗中心接受ERCP的721名AC患者的回顾性分析 (2018年4月 - 2024年4月).
- 专注于住院期间的第一个AC插曲.
- 使用多变量分析来确定独立的风险因素.
主要成果:
- 与ESBL-E (22例) 相比,CAE (113例) 的复发率 (15.9%对4.3%) 和更频繁的广谱抗生素升级 (19.5%对8.7%) 较高.
- 在ESBL-E和非ESBL-E组之间没有观察到显著的临床结果差异.
- 对ESBL-E的独立风险因素包括先前使用抗生素,透析和养老院住宿.
- 对CAE的独立风险因素包括先前的抗生素使用和内镜缩切除术 (EST) 史.
结论:
- 最近的抗生素使用,透析和医疗机构住院与AC中的ESBL-E有关.
- 最近使用抗生素和EST病史与AC中CAE有关.
更多相关视频
08:58Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
09:26Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
Published on: January 22, 2021
相关概念视频
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pyelonephritis II: Diagnostic Studies and Management
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...