脂肪介质干细胞衍生外体与血小板丰富的等离子治疗对光衰老的面部皮肤:一个调查者盲目,分裂面部,非劣等性试验
Blanca Estupiñan1, Karen Ly1, David J Goldberg1,2
1Skin Laser & Surgery Specialists, a Division of Schweiger Dermatology Group, Hackensack, New Jersey, USA.
Journal of cosmetic dermatology
|May 25, 2025
概括
脂肪介质干细胞衍生 (ASC) 外体和富血小板血 (PRP) 同样改善了皮肤衰老迹象. ASC外体提供了PRP的无针替代品,用于皮肤复发.
科学领域:
- 皮肤病学 皮肤病学
- 再生医学是一种再生医学.
- 审美治疗 审美治疗
背景情况:
- 外体和富血小板血 (PRP) 用于皮肤再生和其他皮肤病.
- 没有先前的研究直接比较了这两种再生治疗在美学皮肤病学.
- 外体在治疗光衰老,脱发,亚托皮炎,痕和伤口愈合方面表现有前途.
研究的目的:
- 为了比较脂肪介质干细胞衍生 (ASC) 外体与PRP的疗效和安全性,用于治疗光衰老的面部皮肤.
- 研究ASC外体的潜力,作为PRP在美学皮肤病学中的替代品.
主要方法:
- 进行了一项调查者盲目的,分裂面部临床试验.
- 参与者接受了三次无线电频率微针练习.
- 局部ASC外体应用于脸部的一半,而PRP应用于另一半.
主要成果:
- 无论是ASC外体和PRP都在纹,色差,红斑和皮肤质地方面表现出了相似的改善.
- 组织学检查显示,在两组治疗中,原I和甘氨酸氨基基的增加.
- 在ASC外体和PRP治疗臂之间没有观察到有效性或组织学变化的显著差异.
结论:
- 在美容性皮肤学应用中,ASC外体构成PRP的可行替代品.
- ASC外体可能会吸引那些宁愿避免针头和缩短预约时间的患者.
- 由于不需要进行瘤切割和离心,ASC外体细胞成为一种方便的治疗选择.
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