单细胞转录组揭示了珍珠小米叶的时空热应激反应
Yarong Jin1, Haidong Yan1, Xin Zhu1
1College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
The New phytologist
|May 26, 2025
概括
发展耐热作物对于全球变暖至关重要. 这项研究揭示了珍珠小米血管细胞中的热应激记忆基因是通过清除活性氧物种来增强耐热性的关键.
科学领域:
- 植物生物学 植物生物学
- 基因组学就是基因组学.
- 适应气候变化 适应气候变化
背景情况:
- 全球变暖需要提高耐热度的作物.
- 珍珠小米 (C4植物) 具有耐热性,但细胞机制尚不清楚.
- 了解细胞对热应激的反应对于作物改善至关重要.
研究的目的:
- 在正常和热应激条件下构建珍珠小米叶的单细胞转录组图谱.
- 为了确定关键的细胞类型和热耐受性相关的基因.
- 阐明热应激记忆基因在增强植物弹性中的作用.
主要方法:
- 在不同温度下对珍珠小米叶的单细胞RNA测序.
- 细胞类型的识别和分类使用转录基因数据.
- 权重基因同表达网络分析 (WGCNA) 基因关联.
- 对特定基因突变和过度表达线的表型和生理分析.
主要成果:
- 从珍珠小米叶中生成了20,589个细胞的综合单细胞地图.
- 血管组织细胞在热应激下被确定为关键细胞,表现出许多差异表达和记忆基因.
- 发现热应激记忆基因,特别是UGT73C3,通过减轻活性氧物种积累来增强耐热性.
结论:
- 珍珠小米具有耐热的细胞机制,血管细胞发挥着重要作用.
- 热应激记忆基因对于提高植物对高温的抵抗力至关重要.
- 这项研究为开发适应气候变化的作物提供了宝贵的资源.
相关概念视频
Responses to Heat and Cold Stress
13.9K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.9K
Responses to Salt Stress
13.4K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
13.4K
Transcription
149.3K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
149.3K
Other Stress Responses in Bacteria
72
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
72
Responses to Drought and Flooding
11.1K
Water plays a significant role in the life cycle of plants. However, insufficient or excess of water can be detrimental and pose a serious threat to plants.
11.1K
Thermal Stress
2.6K
If the temperature of an object is changed while it is prevented from expanding or contracting, the object is subjected to stress. The stress is compressive if the object expands in the absence of constraint and tensile if it contracts. This stress resulting from temperature change is known as thermal stress. It can be quite large and can cause damage. To avoid this stress, engineers may design components so they can expand and contract freely. For instance, on highways, gaps are deliberately...
2.6K


