队列选择是否会影响从临床数据中机器学习?
Atefehsadat Haghighathoseini1, Janusz Wojtusiak1, Hua Min1
1George Mason University, Fairfax, VA, USA.
概括
队列选择对机器学习 (ML) 模型的质量和临床数据分析中的公平性产生重大影响. 随意的数据处理决策可能会引入偏见,影响患者的预测结果,特别是在不同人群中.
科学领域:
- 临床信息学 临床信息学
- 医疗保健中的机器学习
- 健康 公平 研究 健康 公平 研究
背景情况:
- 机器学习 (ML) 模型越来越多地用于预测患者的结果.
- 临床数据预处理涉及到可以影响模型性能的关键决策.
- 国家COVID队列协作 (N3C) 为研究这些影响提供了大量数据集.
研究的目的:
- 调查队列选择策略对ML模型质量和公平性的影响.
- 分析任意数据处理决策如何影响模型预测.
- 在ML模型中评估与健康的社会决定因素相关的偏见.
主要方法:
- 使用N3C数据集进行的实验.
- 通过做出四个任意队列选择决定,生成16个不同的数据集.
- 评估数据集尺寸和属性的变化.
- 在不同的队列中评估ML模型的性能.
主要成果:
- 基于包含/排除标准,观察到数据集特征的显著差异.
- 随意队列选择引入偏差的高潜力.
- 在不同队列中训练时,ML模型性能存在实质性的变化.
- 在与不同纳入标准的队列进行比较时,模型性能差异突出.
结论:
- 队列选择是影响ML模型偏差和公平性的关键因素.
- 透明和合理的数据处理决策对于可靠的临床ML至关重要.
- 需要进一步的研究,以减轻ML模型中与健康的社会决定因素相关的偏见.
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