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影响慢性鼻炎患者鼻水的因素
Pranav A Patel1, Ethan M Kallenberger1, Shaun A Nguyen1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
女性性别,没有息肉的CRS,之前的手术和过敏与慢性鼻炎患者的严重鼻后泄漏有关. 了解这些因素可以改善症状管理.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 鼻疾病研究 鼻疾病研究
背景情况:
- 鼻水是慢性鼻炎 (CRS) 的关键症状,但患者的描述各不相同.
- SNOT-22问卷评估了四种不同的鼻水症状.
- 确定影响出院严重性的因素对于有效的患者护理至关重要.
研究的目的:
- 调查与CRS鼻腔排水严重程度相关的患者特异性因素.
- 分析人口统计学和并发症状况对鼻后泄漏 (PND) 严重性的影响.
主要方法:
- 从前性多机构队列研究中对1020名CRS患者进行横截面分析.
- 使用的SNOT-22分数,将严重症状定义为分数≥3.
- 进行了双变量赔率比率计算和多变量回归分析.
主要成果:
- 鼻后泄漏 (PND) 是报告中最严重的症状 (SNOT-22平均得分为2.98).
- 67.3%的患者报告严重的PND.
- 与女性性别相关的严重PND (OR=2.0),没有鼻息肉的CRS (OR=1.5),之前的内镜外科手术 (ESS) (OR=1.5) 和过敏 (OR=1.4).
结论:
- 患有CRS的患者会出现与PND相关的更严重的症状.
- 女性性别,没有鼻的CRS,之前的ESS和过敏是严重PND的显著预测因素.
- 这项研究是第一个将人口统计学和并发症因素与CRS中PND严重程度联系在一起的研究.
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