全球范围审查替代性准备使用的治疗食品
Patrizia Pajak1, Sebsibie Teshome2, Anne Berton1
1Action Against Hunger UK, London, UK.
Maternal & child nutrition
|May 26, 2025
概括
替代性即食治疗食品 (RUTF) 为严重急性营养不良治疗提供了成本节约和更好的成分采购. 研究表明有希望的有效性和接受性,但需要更多关于长期健康和成本效益的数据.
科学领域:
- 营养科学 营养科学
- 全球健康 全球健康
- 食品科学 食品科学 食品科学
背景情况:
- 准备好使用的治疗性食品 (RUTF) 对于治疗严重急性营养不良 (SAM) 至关重要.
- 替代的RUTF配方旨在降低成本,利用当地原料,提高可用性和接受度.
- 全球研究正在探索各种不同的成分,以取代花生和牛奶等传统成分.
研究的目的:
- 识别和分类关于替代RUTF配方的全球证据.
- 评估它们是否符合国际标准.
- 总结关于可接受性,成本,有效性,成本效益和不良事件的数据,确定研究差距.
主要方法:
- 从1999年到2023年6月,对三个数据库和灰色文献进行了范围审查.
- 包括54个来源 (42个同行评审,12个灰色文献).
- 分析了53种已识别的替代RUTF配方,用于6-59个月龄的儿童,无并发性SAM.
主要成果:
- 确定了许多替代RUTF配方,许多成分被测试以取代花生和/或牛奶.
- 这些替代方案表现出一致的接受和有希望的有效性.
- 有限的证据存在于超出人类测量恢复的结果,例如铁状况,认知发育和肠道微生物组影响.
结论:
- 替代RUTF配方显示了降低成本和成分灵活性的潜力.
- 进一步的研究对于评估新型配方符合蛋白质消化性校正氨基酸评分 (PDCAAS) 进行进一步的研究至关重要.
- 需要更多关于成本效益,可访问性,微量营养素状况和长期健康结果的研究.
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