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Updated: Jul 4, 2026

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在患者中检测多基因面板和外体检测的检测率,以前的BRCA1/2结果是负的

Jewel L Wasson1, Trinity N Sprague2, Darcy L Thull2,3

  • 1UPMC Magee Center for Medical Genetics and Genomics, University of Pittsburgh School of Public Health, 300 Halket Street, Suite 1651, Pittsburgh, PA, 15213, USA. wassonjl@upmc.edu.

Familial cancer
|May 26, 2025
PubMed
概括

使用36个基因小组进行更新的基因测试,在8.1%的患者中确定了临床相关的病原体变异,而之前的BRCA1/2测试结果为负. 对于符合条件的患者,建议扩展面板测试,这些患者先前仅对BRCA1/2.2进行了测试.

关键词:
这是一个BRCA负的结果.异源 (exome) 是指外源 (exome) 的一个部分.面板 面板 面板 面板 面板更新了测试测试的更新.

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