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Updated: Jan 18, 2026

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
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对聚醇介导的烯氧化酶抑制的机制性见解:针对胆固醇生物合成的计算模型和实验验证

Emadeldin M Kamel1, Ahmed A Allam2, Hassan A Rudayni2

  • 1Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt. emad.abdelhameed@science.bsu.edu.eg.

Cell biochemistry and biophysics
|May 26, 2025
PubMed
概括

六种天然的多化合物被选为素环氧化酶 (SQLE) 抑制. 黄素,piceatannol和pterostilbene显示出强大的竞争性抑制,突出了它们对代谢障碍的治疗潜力.

关键词:
胆固醇的生物合成酶动力学 酶动力学在体外试验研究研究.分子动力学模拟模型斯克瓦林环氧化酶的使用

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