在COVID-19中的眼部微血管变化:缺氧,D-二次体,IL-6和全身治疗的作用
Magdalena Kal1,2, Michał Brzdęk3,4, Izabella Karska-Basta5,6
1Collegium Medicum, Jan Kochanowski University in Kielce, Kielce, 25-317, Poland.
新冠病毒病2019 (COVID-19) 可能会影响眼睛的微循环. 在康复的患者中,辐射周毛细血管 (RPC) 血管密度 (VD) 与D-二次体和IL-6水平呈反向相关性.
科学领域:
- 眼科医生 眼科 眼科
- 心血管研究研究心血管研究
- 传染性疾病 传染性疾病
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 与内皮功能障碍有关.
- 这种功能障碍可能会损害眼睛组织中的微循环.
研究的目的:
- 评估辐射周毛细血管 (RPC) 血管密度 (VD) 和COVID-19幸存者的因素之间的关联.
- 这些因素包括全身治疗,年龄,缺氧,D-二次体和IL-6水平.
主要方法:
- 对63名COVID-19幸存者的前性研究,在出院后两个月.
- 光学连贯断层扫描血管造影测量RPC VD.
- 评估了与临床数据和生物标志物的相关性.
主要成果:
- 在COVID-19幸存者和对照者之间,RPC VD没有显著差异.
- 氧气治疗与较高的RPC VD相关.
- RPC VD显示与D-二聚合物和IL-6水平的反相关性.
结论:
- 高血压和全身治疗 (甲基,雷梅西维尔) 并没有显著影响RPC VD.
- 特定的RPC区域与D-二元和IL-6相反相关.
- 对COVID-19潜在的长期眼部影响来说,监测周周细胞微血管是至关重要的.
更多相关视频
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
相关概念视频
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Hypertension III: Clinical Manifestations and Diagnostic Studies
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
