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Updated: Sep 20, 2025

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CDC34抑制了巨细胞的细胞活动,并预测癌症中对免疫检查点抑制剂的反应不佳

Xiao-Liang Jie1, Jia-Cong Wei2, Di Wang3

  • 1State Key Laboratory of Molecular Oncology & Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China; Jiangxi Key Laboratory of Oncology (2024SSY06041), Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Cancer Institute, Nanchang, 330029, Jiangxi, China.

Cancer letters
|May 26, 2025
PubMed
概括

细胞分裂周期34 (CDC34) 通过稳定CD47促进癌症免疫逃避,阻碍巨细胞灭菌. 抑制CDC34可能会克服对免疫治疗的耐药性.

关键词:
乳腺癌是什么? 乳腺癌是什么CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47美国疾病预防控制中心 (CDC) 34这就是HIF1α.免疫逃逸是一种免疫逃避.

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