在患有病态肥胖症的个体中,在剖腹产后减少传染性致病率的手术包
Martina Benuzzi1,2, Misa Hayasaka1, Alyssa Savelli1
1EVMS Department of Obstetrics and Gynecology, Macon & Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, Virginia.
American journal of perinatology
|May 26, 2025
概括
对于接受剖腹产的患有病态肥胖症的人来说,手术包增加了抗生素的使用,但没有减少手术部位感染 (SSI),医院再入院或急诊室 (ED) 访问.
科学领域:
- 产科和妇科 产科和妇科
- 手术创新 在外科创新.
- 预防传染病 预防传染病
背景情况:
- 致病性肥胖 (体重指数≥40kg/m2) 增加了剖腹产并发症的风险.
- 手术部位感染 (SSI) 和再入院是这一患者群体的重大问题.
- 标准化外科手术方案或捆绑通常用于减轻手术风险.
研究的目的:
- 评估手术包在减少SSI,医院再入院和急诊室 (ED) 在分娩后六周内访问的有效性.
- 评估包裹对患有病态肥胖症的个体进行剖腹产的伤口并发症的影响.
主要方法:
- 追溯性研究,比较手术捆绑实施前后的结果.
- 该包包括预防性抗生素和48小时的口服塞法莱克辛和美特罗尼达疗程.
- 使用修改Poisson回归来计算调整的相对风险 (aRR) 和95%置信区间 (95% CI) 的统计分析.
主要成果:
- 与干预前期相比,干预后期的阿齐思罗密辛,塞法莱克辛和美特罗尼达的使用增加.
- 没有观察到SSI的显著减少 (aRR:0.92;95%CI:0.66-1.28).
- 医院再入院或急救诊所 (aRR: 0.94;95% CI: 0.80-1.11) 和伤口并发症 (aRR: 1.37;95% CI: 0.96-1.96) 也没有显著下降.
结论:
- 手术包的实施增加了术后抗生素的使用率.
- 手术包没有证明在剖腹产后患有病态肥胖症的个体中,SSIs,医院再入院,急救诊所或伤口并发症的显著减少.
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