创伤性性颗粒瘤与侧向性埃索诺菲利亚:从反应过程到低度CD30 + 淋巴增殖性疾病
Rachelle Wolk1, Denise Trochesset2
1Department of Oral and Maxillofacial Pathology, Radiology, and Medicine, New York University College of Dentistry, 345 East 24th Street, New York, NY, 10010, USA. rh2418@nyu.edu.
Head and neck pathology
|May 26, 2025
概括
创伤性性颗粒瘤与肌性 (TUGSE) 是一种良性口腔病变. 最近的发现表明,TUGSE可能与CD30+T细胞淋巴增殖性疾病 (TLPD) 具有共同特征,尽管在保守的管理下预后仍然很好.
科学领域:
- 口腔病理学 口腔病理学
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 创伤性性颗粒瘤与肌性 (TUGSE) 是一种罕见的口腔粘膜病变.
- 它呈现成人和婴儿 (里加-费德) 形式.
- 它与口服CD30+T细胞淋巴增殖性疾病 (TLPDs) 的关系正在调查中.
研究的目的:
- 审查TUGSE的临床表现,病变发生,组织病理学和治疗.
- 探索TUGSE和口服CD30+TLPDs之间的潜在联系.
- 讨论诊断和治疗方面的影响.
主要方法:
- 关于TUGSE和相关的口腔淋巴增殖性疾病的文献综述.
- 对临床,组织病理学和分子发现的分析.
- 图格斯特征与CD30+TLPD的比较.
主要成果:
- TUGSE呈现为缓慢愈合的,通常在舌头上,模仿状细胞癌.
- 组织病理学揭示了,菌透和肌肉退化;一些病例显示CD30阳性和TCRγ单克隆性.
- 口服CD30+TLPD患者表现出惰的行为和良好的预后,在活检后通常会回归.
结论:
- 图格斯通常是良性的,预后很好,对保守的管理有反应.
- 一些TUGSE病例可能代表CD30+TLPD的光谱,使诊断复杂化.
- 需要进一步的研究来阐明TUGSE和口服CD30+TLPD之间的确切关系.
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